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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
- 保质期:
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
- 英文名:
DMOG;Dimethyloxallyl glycine
- 库存:
12
- 供应商:
爱必信(上海)生物科技有限公司
- CAS号:
89464-63-1
- 规格:
100mg/50mg/200mg/25mg
| 规格: | 100mg | 产品价格: | ¥1056.0 |
|---|---|---|---|
| 规格: | 50mg | 产品价格: | ¥686.0 |
| 规格: | 200mg | 产品价格: | ¥1902.0 |
| 规格: | 25mg | 产品价格: | ¥507.0 |
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抑制剂描述: 产品名称:Dimethyloxaloylglycine(DMOG) 产品别名:见爱必信官网 英文别名:Dimethyloxaloylglycine(DMOG) 靶点:HIF CAS:89464-63-1 纯度:>98% 外观:见爱必信官网 保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. 描述: DMOG is a cell permeable prolyl-4-hydroxylase inhibitor, which upregulates HIF (hypoxia-inducible factor). 溶解性:DMSO : 101.5 mg/mL (579.54 mM) 体外研究: DMOG efficiently suppresses hydroxyproline synthesis in intact cells, but shows only weakly active in the microsomal system. DMOG reduces FGF-2-induced proliferation and cyclin A expression by inhibiting prolyl hydroxylase activity in HPASMC. 体内研究:DMOG inhibits endogenous HIF inactivation, and induces angiogenesis in ischaemic skeletal muscles of mice. Up-regulation of hypoxia-inducible factor-1α by DMOG enhances the cardioprotective effects of ischemic postconditioning in hyperlipidemic rats.
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