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- 爱必信(absin)
- 上海
- abs45153038
- 2025年07月12日
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- 保存条件：
-20°C
- 库存：
99
- 供应商：
爱必信(上海)生物科技有限公司
- 规格：
0.5mg
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试剂描述： 产品名称：Amyloid Precursor Protein, (APP) (721-770) 产品别名： CAS号： 英文别名：Amyloid Precursor Protein, (APP) (721-770) 分子量：5910.7 分子式： 纯度： ≥ 95% 外观：见爱必信官网 保存方法：-20°C 描述： This is amino acids 721 to 770 fragment of the amyloid precursor protein resulting from the g-secretase cleavage of the C-terminus of beta-amyloid precursor protein (APP) at Leu720-Val721. This peptide is also known as CTF50-99. The mutation at Leu723 (L723P) causes familial Alzheimers disease. 应用：
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文献和实验Interaction of the Presenilins with the Amyloid Precursor Protein (APP)
the deposition of amyloid Aβ peptide. The latter is released from its cognate amyloid precursor protein (APP) by a two-step proteolytic conversion: first, proteolysis of APP by β-secretase, which releases the N-terminus of Aβ, and second, conversion
Phosphorylation of Amyloid Precursor Protein (APP) Family Proteins
including fly (4 ), nematode (5 ), and fish (6 ). In mammals, two APP-like genes, amyloid precursor-like protein 1 (APLP1) and 2 (APLP2), have been isolated (7 ,8 ). The amino acid sequences of these APP family proteins are highly conserved, especially
Using an Amyloid Precursor Protein (APP) Reporter to Characterize α-Secretase
Human genetic studies suggest decreasing amyloid peptide (Aβ) levels in the brain could alter the course of Alzheimer’s disease (AD) (1 -4 ). Proteolytic cleavages govern the level of Aβ generated from the amyloid precursor protein (APP). β
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