公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)! 试剂描述: 产品名称:9(Z),11(E),13(E)-十八三烯酸 产品别名: CAS号:506-23-0 英文别名:9(Z),11(E),13(E)-十八三烯酸 分子量:278.4 分子式:C18H30O2 纯度: 外观:见爱必信官网 保存方法:Store at -80° C 描述:9Z,11E,13E-Octadecatrienoic Acid (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid makes up about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. In rats, α-ESA was metabolized and converted to conjugated linoleic acid (9Z,11E-CLA). It has shown potential as a tumor suppressor. In Caco-2 colon cancer cells, α-ESA triggered apoptosis through up-regulation of GADD45, p53, and PPARγ. In DLD-1 cells supplemented with α-ESA, apoptosis was triggered via lipid peroxidation. It also inhibits DNA polymerases and topoisomerases with IC50s ranging from ~5-20 µM for different isoforms of the enzymes. 应用:An inhibitor of DNA polymerases and topoisomerases 产品信息订购:
产品货号 |
产品名称 |
规格 |
价格 |
大包装及货期 |
abs42219580 |
9(Z),11(E),13(E)-十八三烯酸 |
25mg |
5460.00 |
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