描述:Dipyridamole-D20 (Major) is a deuterium labeled derivative of Dipyridamole, which has been shown to act as a selective inhibitor of phosphodiesterase V (PDE 5). This compound has been shown to suppress high glucose-induced osteopontin mRNA expression and protein secretion, as well as inhibit cAMP and cGMP hydrolysis. Research indicates that Dipyridamole is a non-specific nucleoside transport inhibitor with the ability to increase the effects of adenosine in sinoatrial and atrioventricular nodes.
应用:A selective phosphodiesterase V (PDE 5) inhibitor