描述:Cyclosporin C is a highly lipophilic cyclic peptide natural product, a member of the cyclosporin series of antifungal and immunosuppresive compounds - Cyclosporin A and B . The cyclosporins bind the cyclophilin intracellular proteins, highly conserved proteins involved in cis-trans isomerization of peptidyl-prolyl bonds and protein folding.
应用:An immunosuppressive cyclic polypeptide drug commonly used post-transplant to prevent graft rejection from the cytotoxic effects of T-cells