描述:Anpirtoline hydrochloride is a selective agonist of SR-1B. Anpirtoline shows strong selectivity at SR-1B (Ki = 28 nM) over the SR-1A (Ki = 150 nM) and SR-2 (Ki = 1.49 μM) serotonin receptor subtypes. Anpirtoline is also described to produce antagonism at the SR-3 (Ki = 29.5 nM).