描述:17(S)-HpDoHE is a mono-oxygenation product of docosahexaenoic acid in human leukocytes, human whole blood, human glial cells, and murine brain . 17(S)-HpDoHE is generally reduced to 17(S)-HDoHE, a compound that serves as a precursor to 17(S)-resolvins. 17(S)-HDoHE has been shown to inhibit TNF-α-induced interleukin-1β expression in human glioma cells and inhibit TNF-α-induced leukocyte trafficking to the murine air pouch.