13,14-Dihydro-15-keto-prostaglandin F2α is the first substantially accumulating metabolite of PGF2α , that is formed from 15-keto-PGF2α via the 15-hydroxy prostaglandin dehydrogenase pathway. This product has been used to measure the rate of in vivo production of PGF2α, and has been shown to covalently bind to bovine acetylcholine esterase.
应用:A metabolite of PGF2α shown to bind bovine acetylcholine esterase