(±)5-iPF2α-VI is a minor isoprostane constituent. While the isoprostanes derived from arachidonic acid are the best characterized, many other polyunsaturated fatty acids can form isoprostanes. Currently, the most extensively studied of these is 8-isoprostane (8-epi-PGF2α, iPF2α-III), although Type VI isoprostanes are formed in more abundance during natural conditions of oxidative stress. In addition to their greater availability, Type VI isoprostanes are able to form internal lactones which facilitate their extraction and purification from biological samples.
应用:A minor isoprostane constituent able to form internal lactones