Detects a band of approximately 45 kD(Predicted molecular weight: 38 kD) Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
免疫原
Purified recombinant human FAS (C-terminus) protein fragments expressed in E.coli.
性能
形式
Monoclonal Antibody
纯化方法
Affinity Purified
克隆号
4C3
同种型
IgG1
储存/保存方法
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
存储溶液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
修饰
Unmodified
靶标
背景说明
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.