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KLH conjugated synthetic peptide derived from human TNF-alpha:181-235/235
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液态
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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Human, Mouse
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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现货
爱必信(上海)生物科技有限公司
Rabbit
WB=1:500-2000 ELISA=1:500-1000
1mg/ml
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,TNFA, TNFSF2, Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a
TNF alpha抗体
50ul/100ul
规格: | 50ul | 产品价格: | ¥1500.0 |
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规格: | 100ul | 产品价格: | ¥2300.0 |
概述 | |
别名 | TNF alpha抗体;TNF-alpha; APC1; Cachectin; DIF; Differentiation inducing factor; Macrophage cytotoxic factor; MCF; Necrosin; TNF-a; TNF alpha; TNF; TNF Macrophage Derived; TNF Monocyte Derived; TNF Superfamily Member 2; TNFA; TNFSF2; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor Precursor; Tumour Necrosis Factor Alpha; TNFSF1A; TNFA_HUMAN |
宿主 | Rabbit |
特异性 | TNF alpha |
反应种属 | Human, Mouse |
预测反应种属 | Rat; |
应用 | WB=1:500-2000 ELISA=1:500-1000 |
分子量 | Predicted molecular weight: 17kD/26kDa Disclaimer note: The ob served molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
免疫原 | KLH conjugated synthetic peptide derived from human TNF-alpha:181-235/235 |
性能 | |
浓度 | 1mg/ml |
纯化方法 | af finity purified by Protein A |
类型 | Polyclonal Antibody |
同种型 | IgG |
储存/保存方法 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
存储溶液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 信号转导 细胞凋亡 生长因子和激素 细胞因子 |
靶标 | |
背景说明 | Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide stimulated macrophages, and causes tumor necrosis when injected into tumour bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS PAGE under non reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumour Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex. |
细胞定位 | 细胞膜 分泌型蛋白 |
UniProt | P06804 |
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