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Rabbit Anti-TNF alpha Polyclon

al Antibody, TNF alpha抗体
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  • ￥1500 - 2300
  • 爱必信(absin)
  • 上海
  • abs123966
  • 2025年07月16日
  • WB=1:500-2000 ELISA=1:500-1000
  • Rabbit
  • Human, Mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原：

      KLH conjugated synthetic peptide derived from human TNF-alpha:181-235/235

    • 亚型：

      -

    • 形态：

      液态

    • 保存条件：

      Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

    • 克隆性：

      -

    • 标记物：

      -

    • 适应物种：

      Human, Mouse

    • 保质期：

      Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

    • 抗原来源：

      -

    • 目录编号：

      -

    • 级别：

      -

    • 库存：

      现货

    • 供应商：

      爱必信(上海)生物科技有限公司

    • 宿主：

      Rabbit

    • 应用范围：

      WB=1:500-2000 ELISA=1:500-1000

    • 浓度：

      1mg/ml

    • 靶点：

      -

    • 抗体英文名：

      ,TNFA, TNFSF2, Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a

    • 抗体名：

      TNF alpha抗体

    • 规格：

      50ul/100ul

    规格：50ul产品价格：￥1500.0
    规格：100ul产品价格：￥2300.0
    概述  
    别名 TNF alpha抗体;TNF-alpha; APC1; Cachectin; DIF; Differentiation inducing factor; Macrophage cytotoxic factor; MCF; Necrosin; TNF-a; TNF alpha; TNF; TNF Macrophage Derived; TNF Monocyte Derived; TNF Superfamily Member 2; TNFA; TNFSF2; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor Precursor; Tumour Necrosis Factor Alpha; TNFSF1A; TNFA_HUMAN
    宿主 Rabbit
    特异性 TNF alpha
    反应种属 Human, Mouse
    预测反应种属 Rat;
    应用 WB=1:500-2000 ELISA=1:500-1000 
    分子量 Predicted molecular weight: 17kD/26kDa
    Disclaimer note: The ob  served molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
    免疫原 KLH conjugated synthetic peptide derived from human TNF-alpha:181-235/235 
    性能  
    浓度 1mg/ml
    纯化方法 af  finity purified by Protein A
    类型 Polyclonal Antibody
    同种型 IgG
    储存/保存方法 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    存储溶液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    研究领域 肿瘤 细胞生物 免疫学 神经生物学 信号转导 细胞凋亡 生长因子和激素 细胞因子
    靶标  
    背景说明 Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide stimulated macrophages, and causes tumor necrosis when injected into tumour bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS PAGE under non reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumour Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
    细胞定位 细胞膜 分泌型蛋白 
    UniProt P06804

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    • TNFα Promoter Polymorphisms

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    • In situ hybridisation to alpha satellite sequences (chromosome specific)

      solution and replace with mouse anti-biotin antibody diluted 1:100 in blocking solution for 40 minutes at 37C. We currently use DAKO antibody #M0743, 100-200m l per slide. (10) Wash with blocking solution for 10 minutes (11) Incubate with rabbit

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    Rabbit Anti-TNF alpha Polyclonal Antibody, TNF alpha抗体
    ￥1500 - 2300