- ￥1500 - 2300
- 爱必信(absin)
- abs137197
- 上海
- 2025年07月14日
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- Rabbit
- -
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
UCP1抗体
- 抗体英文名：
Rabbit anti-UCP1 Polyclonal Antibody
- 靶点：
-
- 浓度：
1mg/ml
- 应用范围：
WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- 宿主：
Rabbit
- 适应物种：
-
- 保质期：
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
- 抗原来源：
-
- 目录编号：
-
- 级别：
-
- 库存：
现货
- 供应商：
爱必信(上海)生物科技有限公司
- 标记物：
-
- 克隆性：
-
- 保存条件：
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
- 形态：
液态
- 亚型：
-
- 免疫原：
A synthesized peptide derived from Human UCP1(Accession P25874), corresponding to amino acid residues R140-Y161.
- 规格：
50ug/100ug
| 规格： | 50ug | 产品价格： | ￥1500.0 |
|---|---|---|---|
| 规格： | 100ug | 产品价格： | ￥2300.0 |
| 别名 | UCP1抗体;mitochondrial brown fat uncoupling protein, Mitochondrial brown fat uncoupling protein 1, SLC25A7, Solute carrier family 25 member 7, Thermogenin, UCP 1, UCP, UCP1, UCP1_HUMAN, uncoupling protein 1 (mitochondrial, proton carrier), Uncoupling protein 1, |
| 宿主 | Rabbit |
| 特异性 | UCP1 Antibody detects endogenous levels of total UCP1. |
| 反应种属 | Human;Mouse;Rat |
| 应用 | WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000 |
| 分子量 | Predicted molecular weight: 33kD Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 免疫原 | A synthesized peptide derived from Human UCP1(Accession P25874), corresponding to amino acid residues R140-Y161. |
| 浓度 | 1mg/ml |
| 纯化方法 | The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin . |
| 类型 | Polyclonal Antibody |
| 储存/保存方法 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles |
| 存储溶液 | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
| 背景说明 | Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance (By similarity). Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane (PubMed:24196960). However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Regulates the production of reactive oxygen species/ROS by mitochondria (By similarity). |
| 组织特异性 | Brown adipose tissue. |
| 翻译后修饰 | May undergo sulfenylation upon cold exposure. May increase the sensitivity of UCP1 thermogenic function to the activation by noradrenaline probably through structural effects.May undergo ubiquitin-mediated proteasomal degradation. |
| 细胞定位 | Mitochondrion; |
| UniProt | P25874 |
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文献和实验该产品被引用文献
- RNA-Seq reveals miRNA role in thermogenic regulation in brown adipose tissues of goatsXin Liu, Yuehua Zhu, Siyuan Zhan, Tao Zhong, Jiazhong Guo, Jiaxue Cao, Li Li, Hongping Zhang, Linjie Wang
BMC Genomics. 2022 Mar 07 .
影响因子： 3.82
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Rabbit anti-UCP1 Polyclonal Antibody,UCP1抗体
￥1500 - 2300
