CD279, CD279 antigen, hPD 1, hPD l, hPD-1, hSLE1, PD 1, PD1, PDCD 1, PDCD1, PDCD1_HUMAN, Programmed cell death 1, Programmed cell death protein 1, Protein PD 1, Protein PD-1, SLEB2, Systemic lupus erythematosus susceptibility 2. , ,
靶点:
-
浓度:
-
应用范围:
-
宿主:
-
适应物种:
-
保质期:
-
抗原来源:
-
目录编号:
-
级别:
-
库存:
现货
供应商:
爱必信(上海)生物科技有限公司
标记物:
-
克隆性:
-
保存条件:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
形态:
-
亚型:
-
免疫原:
-
规格:
100ul/50ul
规格:
100ul
产品价格:
¥2300.0
规格:
50ul
产品价格:
¥1500.0
别名
PD-1抗体, CD279抗体;CD279, CD279 antigen, hPD 1, hPD l, hPD-1, hSLE1, PD 1, PD1, PDCD 1, PDCD1, PDCD1_HUMAN, Programmed cell death 1, Programmed cell death protein 1, Protein PD 1, Protein PD-1, SLEB2, Systemic lupus erythematosus susceptibility 2. , ,
宿主
Rabbit
特异性
PD-1
反应种属
Human;Mouse;Rat;
预测反应种属
Cow;Horse;Rabbit;
应用
WB=1:500-2000
分子量
Predicted molecular weight: 32kDa Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
免疫原
KLH conjugated synthetic peptide derived from human PD-1:201-288/288
浓度
1mg/ml
纯化方法
affinity purified by Protein A
类型
Polyclonal Antibody
同种型
IgG
储存/保存方法
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
存储溶液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
研究领域
细胞生物 免疫学
背景说明
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
CD279 is an immunoglobulin superfamily member, also known as Programmed Cell Death 1. Programmed Cell Death 1 is expressed on a subset of CD4-CD8 thymocytes, and on activated T and B cells. Programmed Cell Death 1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The Programmed Cell Death 1 ligands, PDL1 (also known as B7H1) and PDL2 (B7DC), are members of the B7 immunoglobulin superfamily.
Sample:
Hela(Human) Cell Lysate at 30 ug
MOLT-4(Human) Cell Lysate at 30 ug
Jurkat(Human) Cell Lysate at 30 ug
Primary: Anti-PD-1 (abs123804) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 32 kD
Observed band size: 55 kD