Within 1 month, 2 to 8 °C under sterile conditions after reconstitution. 12 months from date of receipt, -20 to -80 °C as supplied. Avoid repeated freeze-thaw cycles.
保质期:
-
英文名:
-
库存:
99
供应商:
爱必信(上海)生物科技有限公司
CAS号:
-
规格:
500ug/100ug/50ug
规格:
500ug
产品价格:
¥21000.0
规格:
100ug
产品价格:
¥4600.0
规格:
50ug
产品价格:
¥2500.0
概述
来源
HEK 293
分子量
27.6 kDa (Reducing)
外观
Lyophilized Powder
形态
Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
性能
序列
Protein sequence (P22692, Asp22-Glu258, with C-10*His) DEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQPSDKDEGDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDG
纯度
>95% by SDS-PAGE
内毒素水平
<1 EU/μg(gel-clot)
标记
unconjugated
溶解方法
Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
储存/保存方法
Within 1 month, 2 to 8 °C under sterile conditions after reconstitution. 12 months from date of receipt, -20 to -80 °C as supplied. Avoid repeated freeze-thaw cycles.
靶标
背景说明
IGFBP-4 (insulin-like growth factor binding protein 4) binds to insulin-like growth factor 1 (IGF-1) and IGF-2 with high affinity and inhibits IGF effects in vitro. All members of the IGFBP family bind to IGF-I and IGF-II with approximately equal affinity, but IGFBP-4 binds to IGF2 better than IGF1. It contains a N-terminal domain of IGFBP and a thyroglobulin 1 type domain. IGFBP prolongs the half-life of insulin-like growth factor and has been shown to inhibit or stimulate the stimulative effects of insulin-like growth factor on cell culture. They alter the interaction of IGF with its cell surface receptors. IGFBP-4 is a unique protein that consistently inhibits multiple cancer cells in vivo and in vitro.This product is the recombinant human IGFBP-4 protein expressed from human 293 cells (HEK293).