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- 爱必信(absin)
- 上海
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- 2025年07月16日
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件：
室温保存，有效期5年。
- 保质期：
5年
- 英文名：
PVDF,0.22μm
- 库存：
现货
- 供应商：
爱必信(上海)生物科技有限公司
- CAS号：
-
- 规格：
1卷（30cm*3m）/20张
| 规格： | 1卷（30cm*3m） | 产品价格： | ￥2348.0 |
|---|---|---|---|
| 规格： | 20张 | 产品价格： | ￥525.0 |
| 产品描述 | |
| 描述 | PVDF膜是一种聚偏二氟乙烯(Polyvinylidene Fluoride, PVDF)印迹膜。用于Western blotting、吸附分析、氨基酸分析、N 端蛋白质测序、Dot/Slot blotting、糖蛋白显色和脂多糖分析。最常见用于免疫印迹(WB)时蛋白从胶到膜的转印。 |
| 储存/保存方法 | 室温保存,有效期5年。 |
| 注意事项 | 因制作工艺的原因，用于转印的PVDF膜一面是光滑的，另一面则带有纹理。两面的转印效果是基本相同的，但为保证更高的一致性，建议您以光滑面作为转印面，这样亦无须特别进行膜面的标记。 |
| 生物活性 | |
| 靶点 | TGF-(beta) Receptor |
| In vitro(体外研究) | LY2109761 significantly inhibits the growth of L3.6pl/GLT soft agar colonies in a dose-dependent manner, and results in appr 33% inhibition at 2 μM and 73% inhibition at 20 μM. Targeting TβRI/II kinase activity with LY2109761 (5 μM) almost completely suppresses both the basal and TGF-β1-stimulated migration of L3.6pl/GLT cells. LY2109761 induces a dose-dependent reduction in phosphorylation of Smad-2. HLE endogenous phosphorylation of Smad-2 is inhibited by LY2109761. LY2109761 blocks migration on different ECM proteins and invasion of both HLE and HLF through a 3-dimensional structure. LY2109761 increases E-cadherin mRNA expression after 24 hours and protein levels after 48 hours. LY2109761 pretreatment reduces clonogenic survival in cell cultures of U87MG and T98 following radiation, resulting in an increase in the radiosensitivity with a DEF0.1 of 1.30 and 1.37, respectively. |
| In vivo(体内研究) | LY2109761 (50 mg/kg, p.o.) greatly reduces the tumor volume and increases the median survival duration of the mice to 45.0 days. The mice treated with LY2109761 develop significantly fewer metastatic lesions and, in some of them, no metastatic lesion, as indicated by the GFP signal, can be identified in the abdomen. LY2109761 enhances radiation-induced tumor growth delay in a U87MG subcutaneous xenograft tumor model in BALB/c nude mice. LY2109761 increases survival in an orthotopical CSLC glioblastoma model and enhanced antitumor activity of radiation. |
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- 作者
- 内容
- 询问日期
文献和实验该产品被引用文献
- Small RNA sequencing analysis of exosomes derived from umbilical plasma in IUGR lambsLu Jiawei, Li Huixia, Zheng Xiaomin, Liu Yuan, Zhao Peng
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NEUROCHEMICAL RESEARCH. 2023 Jul 03 .
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ANTI-CANCER DRUGS. 2023 Feb 20 .
影响因子： 2.389
- Downregulated miRNA-491-3p accelerates colorectal cancer growth by increasing uMtCK expressionXingkui Tang, Yukun Lin, Jialin He, Xijun Luo, Junjie Liang, Xianjun Zhu
PeerJ. 2022 Nov 28 .
影响因子： 3.061
- Moderate-Intensity Treadmill Exercise Promotes mTOR-Dependent Motor Cortical Neurotrophic Factor Expression and Functional Recovery in a Murine Model of Crush Spinal Cord Injury (SCI)Zhan, Zuxiong, Pan, Lu, Zhu, Ying, Wang, Yunhang, Zhao, Qin, Liu, Yuan, Li, Sen, Wang, Haiyan, Yang, Ce, Yu, Lehua, Yin, Ying, Tan, Botao
MOLECULAR NEUROBIOLOGY. 2022 Nov 17 .
影响因子： 5.682
- 跑台运动调控mTOR信号通路促进脊髓损伤小鼠运动功能恢复的实验研究詹祖雄
重庆医科大学. 2022 May 01 .
- Post‑treatment with propofol inhibits inflammatory response in LPS‑induced alveolar type II epithelial cellsXilun Yang, Ling Ma
Experimental and Therapeutic Medicine. 2022 Jan 31 .
影响因子： 2.447
- Cyanidin-3-O-glucoside Inhibits the βcatenin/MGMT Pathway by Upregulating miR-214-5p to Reverse Chemotherapy Resistance in Glioma CellsYuan Zhou, Li Chen, Deping Ding, Ziheng Li, Li Cheng, Qiuyun You, Shunbo Zhang
Research Square. 2021 Aug 12 .
- 基于蛋白质组学研究艾纳香油对VECs炎性反应的影响蔡亚玲
贵州大学. 2021 May 01 .
- DOP1 Attenuates Cisplatin-induced Reproductive Injury in Male Mice via the Nrf2/ARE Signaling PathwayWeiwei Yao, Zhaoping Hong, Xuezhen Chen, Biao Liu, Chunbin Lu
International Journal of Science. 2021 Jan 01 ; 1
- MiR-3613-3p from carcinoma-associated fibroblasts exosomes promoted breast cancer cell proliferation and metastasis by regulating SOCS2 expressionYonglei Liu, Yanfei Yang, Junxian Du, Dong Lin, Feng Li
IUBMB Life. 2020 Apr 28 .
影响因子： 5.656
- METTL3/m6A/miRNA-873-5p Attenuated Oxidative Stress and Apoptosis in Colistin-Induced Kidney Injury by Modulating Keap1/Nrf2 Pathway
Jian Wang,Muhammad Ishfaq,Liang Xu,Chunli Xia,Chunli Chen,Jichang Li
Front Pharmacol. 2019 May 15 .
影响因子： 3.831
文献支持
PVDF膜0.22μm
￥525 - 2348
