108-02 ScienCell重组人骨形成蛋白-2 rhBMP-2,Recombinant Human Bone Morphogenetic Protein-2,产品简介: 产品品牌; ScienCell 产品货号:108-02 产品名称:108-02 ScienCell重组人骨形成蛋白-2 rhBMP-2,Recombinant Human Bone Morphogenetic Protein-2 产品规格:2ug
108-02 ScienCell重组人骨形成蛋白-2 rhBMP-2,Recombinant Human Bone Morphogenetic Protein-2, 产品说明: BMP(骨形态发生蛋白)属于信号蛋白的TGF-β。BMP-2是一种有效的骨诱导细胞因子,能够诱导骨和软骨形成,与骨传导载体(如胶原蛋白和合成羟基磷灰石)结合。除了其成骨活性外,BMP-2还参与器官发生,特别是心脏形态发生以及肢芽形成。BMP-2 表达可以在多种组织中发现,包括肺、脾脏、脑、肝、前列腺卵巢和小肠。BMP-2的功能形式是一种26 kDa蛋白质,由两个相同的114个氨基酸多肽链组成,由单个二硫键连接。每个BMP-2单体表示为前体多肽的C末端部分,其中还含有用于分泌的23个氨基酸信号序列和259个氨基酸的前肽。在该前体二聚化后,前肽(也是二硫键连接的同源二聚体)和成熟的BMP-2配体之间的共价键被弗林型蛋白酶切割。
BMPs (Bone Morphogenetic Proteins) belong to the TGF-beta of signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 is also involved in organogenesis, particularly in cardiac morphogenesis, as well as limb bud formation. BMP-2 expression can be found in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine.The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino acid signal sequence for secretion, and a 259 amino acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease.
ScienCell生长添加物产品订购信息: 102-01 重组人干细胞因子 rhSCF,Recombinant Human Stem Cell Factor 2ug 102-02 重组人粒细胞集落刺激因子 rhG-CSF,Recombinant Human Granulocyte Colony Stimulating Factor 2ug 102-03 重组人粒细胞巨噬细胞集落刺激因子 rhM-CSF,Recombinant Human Granulocyte Macrophage Colony Stimulating Factor 5ug 102-09 重组人巨噬细胞集落刺激因子 rhM-CSF,Recombinant Human Macrophage Colony Stimulating Factor 2ug 103-01 重组人肿瘤坏死因子-alpha rhTNF-α,Recombinant Human Tumor Necrosis Factor-alpha 10ug 103-01H 重组人肿瘤坏死因子-alpha,rhTNF--His,Recombinant Human Tumor Necrosis Factor-alpha, His 10ug 103-01v 重组人肿瘤坏死因子-alpha,Variant rhTNF-α variant,Recombinant Human Tumor Necrosis Factor-alpha Variant 10ug 103-04 重组人B细胞激活因子 rhBAFF,Recombinant Human B Cell Activating Factor 5ug 103-08 重组人制瘤素-M227a.a. rhOSM,Recombinant Human Oncostatin-M 227a.a. 2ug 103-08T 重组人制瘤素-M209a.a.,Recombinant Human Oncostatin-M209a.a 2ug 103-09 重组人血管生成抑制因子K1-3 rhAngiostatin K1-3,Recombinant Human Angiostatin K1-3 10ug 103-12 重组人血管内皮抑制素 rhEndostatin,Recombinant Human Endostatin 20ug 104-01 重组人成纤维细胞生长因子-acidic rhaFGF,Recombinant Human Fibroblast Growth Factor-acidic 10ug 104-02 重组人成纤维细胞生长因子-basic rhbFGF,Recombinant Human Fibroblast Growth Factor-basic 10ug 104-07 重组人角质细胞生长因子 rhKGF-1,Recombinant Human Keratinocyte Growth Factor-1 2ug 104-09 重组人成纤维细胞生长因子-9 rhFGF-9,Recombinant Human Fibroblast Growth Factor-9 5ug 104-10 重组人角质细胞生长因子-2 rhKGF-2,Recombinant Human Keratinocyte Growth Factor-2 5ug 104-19 重组人成纤维细胞生长因子-19 rhFGF-19,Recombinant Human Fibroblast Growth Factor-19 5ug 104-21 重组人成纤维细胞生长因子-21 rhFGF-21,Recombinant Human Fibroblast Growth Factor-21 5ug 105-01 重组人胰岛素生长因子-1 rhIGF-1,Recombinant Human IGF-I 20ug 105-01B 重组人DES(1-3)胰岛素生长因子-1 rhIGF-BP3,Recombinant Human DES (1-3) IGF-1 20ug 105-01B3重组人胰岛素生长因子-BP3,Recombinant Human IGF-BP3 5ug 105-03 重组人longR3胰岛素生长因子-1 rhLR3IGF-1,Recombinant Human Long R3 Insulin-like Growth Factor-1 20ug 105-04 重组人表皮生长因子 rhEGF,Recombinant Human Epidermal Growth Factor, 100 ug 100ug 105-05 重组人血管内皮生长因子-165 rhVEGF165,Recombinant Human VEGF165 2ug 106-06 重组人干扰素γ rhIFN-γ,Recombinant Human Interferon-gamma 20ug 107-04 重组人神经营养蛋白-4 rhNT-4,Recombinant Human Neurotrophin-4 2ug 107-08 重组人纤毛神经营养因子 rhCNTF,Recombinant Human Ciliary Neurotrophic Factor 5ug 107-10 重组人神经调节蛋白 rhBTC,Recombinant Human NRG-1 EGF-like domain 10ug 107-11 重组人ErbB3片段 rhErbB3-f,Recombinant Human ErbB3 Fragment 5ug 107-12 重组人β动物纤维 rhBTC,Recombinant Human Betacellulin 5ug 108-02 重组人骨形成蛋白-2 rhBMP-2,Recombinant Human Bone Morphogenetic Protein-2 2ug 108-04 重组人骨形成蛋白-4 rhBMP-4,Recombinant Human Bone Morphogenetic Protein-4 2ug 108-07 重组人骨形成蛋白-7 rhBMP-7,Recombinant Human Bone Morphogenetic Protein-7 2ug 108-08 重组人骨保护素 rHuOPG-Fc,Recombinant Human Osteoprotegerin/Fc Chimera 10ug 108-09 重组人NOGGIN蛋白 rhNOGGIN,Recombinant Human NOGGIN 5ug 301-01 重组人生长激素 rhGF,Recombinant Human Growth Hormone 20ug