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Von Frey Hair纤毛机械刺激针用来测量动物的触觉阈疼痛阈机械痛阈测量仪，主要用于评估皮肤的触觉，是非常受欢迎的非侵入式实验器材。Von Frey Hairs尼龙丝的粗细及伸出长度决定提供刺激力的大小。实验时，根据实际情况选定粗细当得的 Von Frey Hairs纤毛机械刺激针，调节适当Von Frey Hair纤毛机械刺激针的伸出长度，垂直地刺激皮肤，可通过调节伸长、更换Von Frey Hair 纤毛机械刺激针 调整刺激力大小，直到 Von Frey Hair 纤毛机械刺激针弯曲。多次测试之后套入公示，测量得到机械痛阈值。
Von Frey纤维丝在小动物触觉阈值测试中的应用：
Von Frey纤毛机械刺激针可提供0.008g-300g的触觉刺激力。（进行von Frey test使用方便，可对多种动物进行定量的机械痛阈或触觉阈测量，敬请来电咨询）
Von Frey Hairs纤毛机械刺激针尼龙丝的粗细及伸出长度决定提供触觉von Frey test刺激力的大小。实验时，根据实际情况选定粗细当得的触觉测试Von Frey Hairs纤毛机械刺激针，调节适当的伸出长度，垂直地刺激皮肤，可通过调节伸长、更换触觉尼龙丝调整刺激力大小，直到触觉测量尼龙丝弯曲。当啮齿类动物得爪受到一个机械痛阈或触觉阈，它们会缩回反射。该触觉测试可应用于大、小鼠的足底机械痛阈或触觉阈测量。
另外: Von Frey Hairs纤毛机械刺激针使用时可选配凿孔工作台，其触觉测量网筛孔是利用激光切冲而成的方形孔，尺寸为5×5mm2 ，触觉测量孔间距约为1mm，这对受试动物而言是一个舒适的环境，也便于操作人员观察动物的足底触觉感应区域。该凿孔台经涂层处理，便于清洁且不易被腐蚀。
可配合测试支架和大小鼠测试笼，对动物足底进行测试：
小鼠与测试平台
小鼠与测试平台
十字测试网格
加高型测试支架
标准型测试支架与电子式测痛仪
根据需求，可以配合45°倾角的镜子使用，让观察更加方便；
也可对人体或动物的其他部位的触觉反应，进行测试：
测痛实验大鼠固定器
可用于大鼠的面部、背部、腹部的刺痛实验；
可根据老鼠的体重订做合适的尺寸；
Von Frey纤维丝在人体手部、足部触觉测试中的应用：
Von Frey纤毛机械刺激针也可叫做Touch-Test单丝测试盒、Semmes-Weinstein触觉测量尼龙丝，能测试和评估感觉水平，每个Touch-Test™单丝测试笔被单独校准，力量值在5%的标准偏差范围内，以此可测试感觉水平。
利用Touch-Test™单丝感觉测试套装来测试感觉水平，获取客观数据，可以准确报告正在减少或回复的感觉状态；
测试根据预先设定的力的5%的标准偏差进行的；
当达到峰值力阈值时，单丝测试笔的单丝呈弯曲形状；
独特的手柄设计使Touch-Test™单丝测试笔可以轻松地打开90°角进行测试；关闭时，测试笔可以被安全地放在口袋或手提箱中，以确保可以在不使用时保护单丝；
单丝测试笔手柄上的手指凹痕提供了牢固且舒适的握持手感；
单丝测试笔手柄上都标有相应的颜色编码的压力水平；
测试结果可以记录在另行出售的手部或脚部筛查表格（NC12750-1和NC12749）上；
有5件套手部套件装，6件套足部套件装和20件套全套套件装可供选择；
每种规格的套件都有保护套，带使用说明。；
用于替换的5.07（10g）的单丝测试笔可单独出售，5.07（10g）表明足部的保护性感觉丧失；
不同颜色代码代表不同的压力级别，规格及所代表的的力量分别为：
1.65（0.008克）、2.36（0.02克）、2.44（0.04克）、2.83（0.07克）、3.22（0.16克）、3.61（0.4克）、3.84（0.6克）、4.08（1.0克）、4.17（1.4克）、4.31（2.0克）、4.56（4.0克）、4.74（6.0克）、4.93（8.0克）、5.07（10.0克）、5.18（15.0克）、5.46（26.0克）、5.88（60.0克）、6.10（100.0克）、6.45（180.0克）、6.65（300.0克）。
正常为1.65~2.83（Normal)
轻触觉减退为3.22~3.61（Diminished Light Touch)
保护性感觉减退为3.84~4.31（Diminished Protective Sensation)
保护性感觉丧失为4.56~6.45（Diminished Protective Sensation）
6.65用于深层感觉检测（Deep Pressure Sensation Only）
有手部感觉测试型、足部感觉测试型和全规格测试型可供选择：
手部套件包含：2.83, 3.61, 4.31, 4.56 ,6.65 五种单丝测试；
足部套件包含：2.83, 3.61, 4.31, 4.56, 5.07 , 6.65六种单丝测试；
全规格套件包含：所有二十种单丝测试---推荐配置
产品型号如下，敬请来电订购：
NC12772 Touch-Test 单丝测试套件, 手部
NC12773 Touch-Test 单丝测试套件, 足部
NC12775-99 Touch-Test 单丝测试套件, 全套20件---推荐
电子式测痛仪应用于人体研究时候，可实时读取0-800g的具体数据：
型号：38450
敬请来电咨询。
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文献和实验[HTML] Fine‐touch pressure thresholds in the adult penis
ML Sorrells, JL Snyder, MD Reiss, C Eden… - BJU …, 2007 - Wiley Online Library
... The fine-touch sensitivity of 19 locations on the penis was measured using Semmes-Weinstein
monofilament touch-test sensory evaluators (North Coast Medical Supply, Morgan Hill, CA,
USA) [15–17] to create a penile sensitivity map (Figs 1 and 2). image ...
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[HTML] An experimental paradigm for the prediction of Post-Operative Pain (PPOP)
R Landau, JC Kraft, LY Flint, B Carvalho… - JoVE (Journal of …, 2010 - jove.com
... Pathway - Pain and Sensory Evaluation System, Medoc Advanced Medical Systems, B–kel 14L
Hot Tub, Boekel Scientific, 180g Touch-Test Sensory Evaluator, North Coast Medical, Morgan
Hill, California, Electronic von Frey, Bioseb, Cedex, France, References. ...
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Auditory grip force feedback in the treatment of writer's cramp
B Baur, W Fürholzer, C Marquardt… - Journal of Hand Therapy, 2009 - Elsevier
... The average age was 54.3 (±8.0) years. The mean duration of WC was 12.6 ± 16.9 years (range
0.5–48 yr). Touch sensibility measured by two-point discrimination for all patients was within
the normal range (mean: 2.6 ± 0.5 mm; Touch-Test, North Coast Medical, Inc.). Table 1. ...
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Ankle equinus deformity and its relationship to high plantar pressure in a large population with diabetes mellitus
LA Lavery, DG Armstrong… - Journal of the American …, 2002 - Am Podiatric Med Assoc
... A lower-extremity sensory examination was conducted using a 10-g Semmes-Weinstein
monofilament (Touch-Test Sensory Evaluator, North Coast Medical Inc, Morgan Hill, California)
and vibration perception threshold testing (VPT Tester, Salix Medical, San Antonio, Texas ...
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Human experimental pain models 3: heat/capsaicin sensitization and intradermal capsaicin models
JG Modir, MS Wallace - Analgesia: Methods and Protocols, 2010 - Springer
... 4. Touch-Test Sensory Filament 5.46 (North Coast Medical, Morgan Hill, CA). 5. 26-g von Frey
hair (Semmes-Weinstein monofilaments, Stoelting, IL). 6. ... 3. Touch-Test Sensory Filament 5.46
(North Coast Medical). 4. 26-g von Frey hair (Semmes-Weinstein monofilaments). 5. ...
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Five-year follow-up of a cordotomy
JJ Meeuse, A Vervest, JH van der Hoeven… - Pain Research and …, 2008 - hindawi.com
... The function of the anterior spinothalamic tract was studied using a Touch-Test kit (North Coast
Medical Inc, USA). ... Figure 2) The touch perception threshold was evaluated by using
Semmes-Weinstein monofilaments (Touch-Test kit; North Coast Medical Inc, USA). ...
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Comparison of dynamic (brush) and static (pressure) mechanical allodynia in migraine
C LoPinto, WB Young, A Ashkenazi - Cephalalgia, 2006 - Wiley Online Library
... allodynia (BA) was tested by gently applying a folded 4 × 4-in gauze pad to the skin, 10 times
at a frequency of 2/s as we previously described (7). Pressure allodynia (PA) was tested by
applying von Frey hairs (VFH) (Touch-Test™ Sensory Evaluators; North Coast Medical, Inc. ...
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Effects of vacuum-compression therapy on healing of diabetic foot ulcers: randomized controlled trial
A Akbari, H Moodi, F Ghiasi… - Journal of …, 2007 - search.proquest.com
... We assessed sensory status using a biothesiometer (Bio-Medical Instrument Company, Newbury,
Ohio) and by applying a Semmes-Weinstein 10 g monofilament (Touch-Test Sensory Evaluator,
North Coast Medical, Inc, Morgan Hill, California) to the plantar surface of the foot. ...
Cited by 59 Related articles All 13 versions Cite Save
Tactile sensation and occlusal loading condition of mandibular premolars and molars
T Ogawa, T Suzuki, N Oishi, X Zhang, I Naert, K Sasaki - Odontology, 2011 - Springer
... The TDT of each tooth was measured by calibrated monofilaments (Touch-Test ® ,
North Coast Medical, CA, USA) with 20 different diameters corresponding to 20 target
forces (0.008–300 g) [10]. Tactile stimulation was applied ...
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Antinociceptive effect of CNS peroxynitrite scavenger in a mouse model of orofacial pain
JF Yeo, SF Ling, N Tang, WY Ong - Experimental brain research, 2008 - Springer
... The carrageenan injected area of the face was probed with a von Frey hair of 4.08 log units
(Touch-Test Sensory Evaluator, North Coast Medical, Morgan Hill, USA) and the number of
immediate face wash strokes (previously shown to be a specific indicator of nociceptive ...
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Stability and morbidity of Le Fort I osteotomy with bioresorbable fixation: a randomized controlled trial
LK Cheung, IHS Yip, RLK Chow - … journal of oral and maxillofacial surgery, 2008 - Elsevier
... The static light touch test was performed using a Touch-Test Sensory Evaluator kit
(NC12775, North Coast Medical Inc., CA, USA). Individual filaments of ascending
diameters were pressed against the infra-orbital skin until they bent. ...
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Acidic buffer induced muscle pain evokes referred pain and mechanical hyperalgesia in humans
LAF Law, KA Sluka, T McMullen, J Lee… - Pain, 2008 - Elsevier
... Cutaneous sensation was measured at the same six sensory test locations using
a single 100 g von Frey filament (Touch Test 6.10, North Coast Medical, Inc., USA).
Following three perpendicular stimulations to the skin surface ...
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Skin temperatures as a one-time screening tool do not predict future diabetic foot complications
DG Armstrong, LA Lavery… - Journal of the …, 2003 - Am Podiatric Med Assoc
... 15, 16 Peripheral neuropathy was evaluated using a 10-g Semmes-Weinstein monofilament
(Touch-Test Sensory Evaluator; North Coast Medical Inc, Morgan Hill, California) and vibration
perception threshold testing (VPT Tester; Xilas Medical Inc, San Antonio, Texas).17 ...
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[HTML] Relative sensory sparing in the diabetic foot implied through vibration testing
T O'brien, J Karem - Diabetic foot & ankle, 2013 - diabeticfootandankle.net
... To diagnose neuropathy, each test subject underwent testing with a 5.07/10 g Semmes-Weinstein
monofilament test (SWMT) (Touch-Test; North Coast Medical, Morgan Hill, CA), biothesiometer
(Biomedical Instruments, Newbury, OH), sharp/dull discrimination test, and ETF (O ...
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Disease management for the diabetic foot: effectiveness of a diabetic foot prevention program to reduce amputations and hospitalizations
LA Lavery, RP Wunderlich, JL Tredwell - Diabetes research and clinical …, 2005 - Elsevier
... We identified sensory neuropathy from evaluation with a 10 gm Semmes-Weinstein
monofilament (Touch-Test Sensory Evaluator, North Coast Medical Inc., Morgan Hill,
CA) and Biothesiometer-VPT Meter (Xilas Medical, San Antonio, TX). ...
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