CBX3 单克隆抗体

Western Blot（WB）已验证样本:Hela,3T3,PC12
免疫荧光（IF）已验证样本:Human colon carcinoma,Mouse spleen

WB 1:500-2000, IHC 1:50-300

Monoclonal

IgG

Recombinant Protein of HP-1γ

CBX3

CBX 3;CBX3;CBX3;Chromobox homolog 3 (HP1 gamma homolog;Drosophila);Chromobox homolog 3;Chromobox protein homolog 3;GAMMA;HECH;Heterochromatin like protein 1;Heterochromatin protein 1 homolog gamma;Heterochromatin protein HP1 gamma;HP1 gamma;HP1 gamma homolog;HP1Hs gamma;Modifier 2 protein抗体

Q13185

24kDa

Nucleus. Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis.

1 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Protein A purification

Cancer; Epigenetics and Nuclear Signaling

Clone:6A4

Unconjugated

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks.