Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide,pH7.3.
规格:
50 μL
产品名称:
DNA topoisomerase II alpha (TOP2A) Rabbit pAb
货号:
A0726
背景:
This gene encodes a DNA topoisomerase; an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation; chromatid separation; and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another; thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form; alpha; is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
别名:
TOP2A; TOP2; TP2A
宿主:
Rabbit
反应物种:
Human
验证应用:
IF
免疫原:
Recombinant fusion protein containing a sequence corresponding to amino acids 1314-1503 of human DNA topoisomerase II alpha (TOP2A) (NP_001058.2).
基因ID:
7153
存储缓冲液:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide;pH7.3.
图片:
Immunofluorescence - DNA topoisomerase II alpha (TOP2A) Rabbit pAb (A0726)