Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
规格:
200 μL
产品名称:
STAT6 Rabbit pAb
货号:
A0755
背景:
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors; STAT family members are phosphorylated by the receptor associated kinases; and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L); which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells; expression of cell surface markers; and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
别名:
D12S1644; IL-4-STAT; STAT6B; STAT6C; STAT6
宿主:
Rabbit
反应物种:
Human; Mouse; Rat
验证应用:
WB; IF
免疫原:
A synthetic peptide corresponding to a sequence within amino acids 550-650 of human STAT6 (NP_003144.3).
基因ID:
6778
存储缓冲液:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide;50% glycerol;pH7.3.