Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
规格:
100 μL
产品名称:
SLC27A2 Rabbit pAb
货号:
A1077
背景:
The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity; subcellular localization; and tissue distribution; all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters; and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain; branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney; and is present in both endoplasmic reticulum and peroxisomes; but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.