Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
规格:
50 μL
产品名称:
ALDH18A1 Rabbit pAb
货号:
A12247
背景:
This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate; a critical step in the de novo biosynthesis of proline; ornithine and arginine. Mutations in this gene lead to hyperammonemia; hypoornithinemia; hypocitrullinemia; hypoargininemia and hypoprolinemia and may be associated with neurodegeneration; cataracts and connective tissue diseases. Alternatively spliced transcript variants; encoding different isoforms; have been described for this gene.