Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
规格:
200 μL
产品名称:
ATM Rabbit pAb
货号:
A15645
背景:
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus; it functions as a regulator of a wide variety of downstream proteins; including tumor suppressor proteins p53 and BRCA1; checkpoint kinase CHK2; checkpoint proteins RAD17 and RAD9; and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia; an autosomal recessive disorder.
别名:
AT1; ATA; ATC; ATD; ATDC; ATE; TEL1; TELO1; ATM
宿主:
Rabbit
反应物种:
Human; Rat
验证应用:
IF
免疫原:
A synthetic peptide corresponding to a sequence within amino acids 1900-2000 of human ATM (NP_000042.3).
基因ID:
472
存储缓冲液:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide;50% glycerol;pH7.3.