Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
规格:
50 μL
产品名称:
CD22 Rabbit pAb
货号:
A5790
背景:
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding; followed by varying numbers of Ig-like C2-type domains. Human Siglec-2; also known as B-cell antigen CD22 or Blymphocyte cell adhesion molecule (BL-CAM); is a B-cell restricted glycoprotein that is expressed in the cytoplasm of progenitor B and pre-B cells and on the surface of mature B cells. Two distinct human Siglec2/CD22 cDNAs that arise from differential RNA processing of the same gene have been isolated. Siglec2/CD22 is an adhesion molecule that preferentially binds alpha 2;6- linked sialic acid on the same (cis) or adjacent (trans) cells. Interaction of CD22 with trans ligands on opposing cells was found to be favored over the binding of ligands in cis.
别名:
CD22; SIGLEC-2; SIGLEC2
宿主:
Rabbit
反应物种:
Human; Mouse
验证应用:
WB; IF
免疫原:
Recombinant fusion protein containing a sequence corresponding to amino acids 708-847 of human CD22 (NP_001762.2).
基因ID:
933
存储缓冲液:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide;50% glycerol;pH7.3.