Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
规格:
200 μL
产品名称:
SF3B3/SAP130 Rabbit pAb
货号:
A6146
背景:
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b; together with splicing factor 3a and a 12S RNA unit; forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex; and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification; transcription; splicing; and DNA repair.
别名:
SF3B3; RSE1; SAP130; SF3b130; STAF130
宿主:
Rabbit
反应物种:
Human; Mouse; Rat
验证应用:
WB; IHC; IF
免疫原:
Recombinant fusion protein containing a sequence corresponding to amino acids 948-1217 of human SF3B3/SAP130 (NP_036558.3).
基因ID:
23450
存储缓冲液:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide;50% glycerol;pH7.3.