Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 50% glycerol,0.2%BSA,0.03%PC300,pH7.3.
规格:
25 μg
产品名称:
ABflo? 488 Rabbit anti-Human CD86 mAb
货号:
A21940
背景:
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells; and it is the ligand for two proteins at the cell surface of T cells; CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.