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MCE 国际站:Osteogenesis Compound Library
Ossification is a tightly regulated process, performed by specialized cells called osteoblasts. Dysregulation of this process may cause inadequate or excessive mineralization of bones or ectopic calcification, all of which have grave consequences for human health. Osteoblasts play important roles in the process of osteogenesis and prevention of osteonecrosis. Osteoblast formation and bone formation are regulated by hormones, growth factors, cytokines, etc. MCE offers a unique collection of 419 bone formation compounds with identified and potential inducing osteogenesis activity. MCE bone formation compound library is a useful tool for the study of bone disease drugs and pharmacology.
Description & Advantages:
• A unique collection of 419 bone formation compounds for high throughput screening (HTS) and high content screening (HCS).
• A useful tool for the study of bone disease drugs and pharmacology.
• Target diverse, medicinally active and cell permeable.
• Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.
• More detailed compound information with structure, IC50, and other chemical & biological data.
• High purity and quality validated by NMR and LC/MS.