Temafloxacin hydrochloride

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Temafloxacin hydrochloride

CAS No. : 105784-61-0

MCE 国际站：Temafloxacin hydrochloride

产品活性：Temafloxacin (TMFX) hydrochloride 是一种口服有效的喹诺酮类广谱抗菌剂。Temafloxacin hydrochloride 对下呼吸道和泌尿生殖道感染具有较好的耐受性。

研究领域：Anti-infection

作用靶点：Antibiotic  |  Bacterial

In Vitro: Temafloxacin hydrochloride (0-64 µg/mL; 18-24 h) shows good antibacterial activity for gram-positive/negative bacteria, with MIC ranges of <0.004-0.5, 0.5-2 and 0.06-0.25 µg/mL for E. coli, P. aeruginosa, and S. aureus, respectively.

In Vivo: Temafloxacin hydrochloride (6.25, 25, 100 mg/kg; p.o.; single) shows good inhibitory activity to murine pyelonephritis.
Temafloxacin hydrochloride (100 mg/kg; p.o. or s.c.; single) shows rapid gastrointestinal absorption, and has excellent tissue and body fluid penetration and concentration (except for central nervous system (CNS)).

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