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Please store the product under the recommended conditions in the Certificate of Analysis.
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MedChemExpress LLC
- CAS号:
3033645-30-3
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询盘
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Chitin synthase inhibitor 7
MCE 国际站:Chitin synthase inhibitor 7
产品活性:Chitin synthase inhibitor 7 (compound 9c) 是一种有效的 chitin synthase (CHS) 抑制剂,其 IC50 值为 0.37 mM,Chitin synthase inhibitor 7 对耐药真菌具有广谱抗真菌活性。Chitin synthase inhibitor 7 可用于真菌感染的研究。
研究领域:Anti-infection
作用靶点:Fungal
In Vitro: Chitin synthase inhibitor 7 (compound 9c; 300 μg/mL) inhibits chitin synthase (CHS) activity with an inhibition percentage (IP) value of nearly 70% .
Chitin synthase inhibitor 7 (1-512 μg/mL) has antifungal activity against four strains with minimum inhibitory concentration (MIC) values of 128, 256, 256, and 256 μg/mL for C. albicans, A. flavus, A. fumigatus, and C. neoformans, respectively.
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文献和实验Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of all isoforms of nitric oxide synthase, the enzyme that synthesizes nitric oxide from arginine. Elevated plasma concentrations of ADMA are associated with hypertension
Cloning and Expression of Human Inducible Nitric Oxide Synthase
NO synthase (NOS) pathway was first characterized and cloned in murine macrophages (1 –3 ). Activation with lipopolysaccharide (LPS) and interferon-γ (IFN-γ) was uniformly used in these studies to increase inducible (i) NOS expression and improve cloning
Acetolactate synthase (ALS) is an enzyme in the biosynthetic pathway for branched-chain amino acids, and bispyribac-sodium (BS), a pyrimidinyl carboxy herbicide, is a well-known inhibitor of ALS activity. However, it appears that a mutated
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