DL-β-Hydroxybutyryl coenzyme A

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DL-β-Hydroxybutyryl coenzyme A lithium

CAS No. : 103404-51-9

MCE 国际站：DL-β-Hydroxybutyryl coenzyme A lithium

产品活性：DL-β-Hydroxybutyryl coenzyme A lithium 是丁酸发酵以及赖氨酸和色氨酸代谢的中间体，由 β-羟基丁酸通过短链-CoA 合成酶生成。

研究领域：Metabolic Enzyme/Protease

作用靶点：Endogenous Metabolite

In Vitro: DL-β-Hydroxybutyryl coenzyme A lithium (β-Hydroxybutyryl-CoA) can be produced as an intermediate metabolite via the mitochondrial pathway, where impaired mitochondrial function in cancer cells leads to the accumulation of it. At the same time, DL-β-Hydroxybutyryl coenzyme A lithium can also be produced via the fatty acid β-oxidation, which is accelerated by starvation and fasting, leading to the accumulation of it and thus to diseases caused by certain metabolic adaptations.
DL-β-Hydroxybutyryl coenzyme A lithium (β-Hydroxybutyryl-CoA) can act as a cofactor for lysine β-hydroxybutyrylation (Kbhb), with elevated levels of histone Kbhb in a streptozotocin (STZ)-induced type 1 diabetes mellitus (T1DM) mouse model.

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