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- 2025年12月05日
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- 英文名：
JNJ-39933673
- 库存：
货期：询盘
- 供应商：
MedChemExpress LLC
- CAS号：
1003005-29-5
- 规格：
询盘
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TA-1887
CAS No. : 1003005-29-5
MCE 国际站：TA-1887
产品活性：TA-1887 (JNJ-39933673) 是一种高效的、选择性的、具有口服活性的 SGLT2 抑制剂 (IC50: 1.4 nM)，具有降血糖作用。TA-1887 可用于糖尿病研究。
研究领域：Membrane Transporter/Ion Channel
作用靶点：SGLT
In Vivo: TA-1887 (30 mg/kg, oral administration, rats) induces glucose excretion over a 24 h period of 2502 mg per 200 g body weight.
TA-1887 (3 mg/kg, oral administration) reduces blood glucose levels without influencing food intake in hyperglycemic high-fat diet-fed KK (HF-KK) mice.
TA-1887 (30 mg/kg/day, oral gavage for 2 weeks) significantly reduces GFR (glomerular filtration rate) in BSA-overloaded diabetic mice.
TA-1887 (0.01% w/w in chow, HF diets fed mice) antagonizes diabetic cachexia and decreases mortality in diabetic mice.
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文献和实验For direct gene transfer of tibialis anterior (TA) muscle in mice: It is optimal to use 6-8 week old mice (weight 19-21 gm). Females give better immune responses for the hepatitis B surface antigen, and this might be true
Real-Time PCR Quantification Using Cloned Standards and Multiple Housekeeping Genes
for RNA quantitation. Biotechniques 29:332-7, 2000. Thellin O, Zorzi W, Lakaye B, De Borman B, Coumans B, Hennen G, Grisar T, Igout A, Heinen E. Housekeeping genes as internal standards: use and limits. J Biotechnol 75:291-5, 1999. Vandesompele
ESCO-0480 ESCO 螺丝刀EA557C-75 螺丝刀 EA557C-75
EA538RA-29 EA538RA-29 ESCO-0454 ESCO 锁片EA951MA-44 EA951MA-44 ESCO-0453 ESCO 螺丝EA442AA-12 EA442AA-12 ESCO-0452 ESCO 螺丝刀EA642HV-5.5 EA642HV-5.5 ESCO-0451 ESCO 螺丝刀EA642HV-5 EA642HV-5 ESCO-0450 ESCO 放大镜EA756AC-2 EA756AC-2 ESCO-0449
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