113-O12B is a disulfide bond-containing cationic lipidoid.{65448} It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA. Subcutaneous administration of LNPs containing 113-O12B and encapsulating an mRNA reporter accum
库存:
10 mg, 25 mg, 5 mg
供应商:
Cayman
CAS号:
2803699-72-9
A cationic lipidoid; has been used in the generation of LNPs for the delivery of mRNA; subcutaneous administration of LNPs containing 113-O12B and encapsulating an mRNA reporter accumulate specifically in mouse lymph nodes; LNPs containing 113-O12B and encapsulating mRNA encoding ovalbumin reduce tumor growth and increase the number of tumoral CD8+ T cells, M1-like macrophages, and activated dendritic cells in an ovalbumin-expressing B16/F10 murine melanoma model