Angiotensin A is an angiotensin II type 1 (AT1) and AT2 receptor agonist and active metabolite of the peptide hormone angiotensin II (Item No. 17150).{69091} It is formed from angiotensin II via decarboxylation of the N-terminal aspartate residue. Angio
英文名:
Ala-Arg-Val-Tyr-Ile-His-Pro-Phe|Des[Asp1]-[Ala1]-Ang II
库存:
10 mg, 25 mg, 5 mg
供应商:
Cayman
规格:
This biochemical is available in the following size(s) 10 mg, 5 mg, 500 µg - Please inquire
An AT1 and AT2 receptor agonist and active metabolite of angiotensin II; binds to AT1 and AT2 receptors in HEK293 cells expressing the rat receptors (IC50s = 0.29 and 0.12 nM, respectively, in radioligand binding assays); induces calcium mobilization in VSMCs (EC50 = 100 nM); increases the perfusion pressure in isolated perfused rat kidney (EC50 = 443 nM), an effect that can be reversed by EXP-3174; the plasma Ang A/Ang II ratio is increased in patients with end-stage renal failure; serum levels are decreased in patients with pulmonary arterial hypertension