- ￥3730 - 27400
- TargetMol
- 美国
- T39459
- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
THZ-P1-2
- 库存：
10
- 供应商：
TargetMol
- CAS号：
2058075-45-7
- 规格：
25 mg/50 mg/5 mg/100 mg
| 规格： | 25 mg | 产品价格： | ￥13900.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥18300.0 |
| 规格： | 5 mg | 产品价格： | ￥3730.0 |
| 规格： | 100 mg | 产品价格： | ￥27400.0 |
Product Introduction
Bioactivity
英文名:THZ-P1-2
描述:THZ-P1-2 is a novel, specific inhibitor of PI5P4K that effectively targets PI5P4Kα. With an IC 50 of 190 nM, THZ-P1-2 selectively inhibits PI5P4Kα by forming covalent bonds with cysteine residues located on a disordered loop present in PI5P4Kα/β/γ. This mechanism not only disrupts autophagy but also elevates TFEB signaling. Moreover, THZ-P1-2 exhibits potent anticancer effects in leukemia cell lines, making it a promising candidate for therapeutic applications.
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文献和实验96 Well Mating Protocol platewise
Chemicals needed: Glucose L-( )-Arabinose Sigma Cat # A3256 L-Rhamnose Sigma cat # R3875 Cb (carbenicillin) Sigma cat # 1389 DL-p-Chlorophenylalanine Sigma cat # C6506 Media Recipes: YEG recombination plates
96 Well Mating Protocol platewise
Chemicals needed:Glucose L-(+)-Arabinose Sigma Cat # A3256 L-Rhamnose Sigma cat # R3875 Cb (carbenicillin) Sigma cat # 1389DL-p-Chlorophenylalanine Sigma cat # C6506 Media Recipes: YEG recombination plates:1 liter Milli Q water5 g yeast
and 0.0125% bromophenol blue) and mix well. 3) Denature the ladder in loading buffer at 70°C for 10 minutes. Keep on ice for 1-2 minutes to quench. 4) Load ladder and your RNA samples on the pre-run gel from Step 1. 5) Perform
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