Powder: -20°C for 3 years In solvent: -80°C for 2 years
英文名:
C2-8
库存:
10
供应商:
TargetMol
CAS号:
300670-16-0
规格:
50 mg
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产品名称:C2-8 产品别名:C2-8;C2-8
产品介绍:C2-8 is an inhibitor of polyglutamine (polyQ) aggregation (IC50s = 25 and 0.05 μM for recombinant HDQ51 and in PC12 cells, respectively). It also inhibits polyQ aggregation in organotypic hippocampal slice cultures isolated from R6/2 transgenic mice and reduces neurodegeneration in a dose-dependent manner in a Drosophila model of Huntington's disease. C2-8 (100 and 200 mg/kg) reduces huntingtin aggregate size, reduces neuronal atrophy, and improves motor performance in a rotarod test in the R6/2 transgenic mouse model of Huntington's disease. 纯度:N/A CAS:300670-16-0
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