- ￥1240 - 9690
- TargetMol
- 美国
- T38196
- 2025年07月14日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Prostaglandin F2α isopropyl ester
- 库存：
10
- 供应商：
TargetMol
- CAS号：
53764-90-2
- 规格：
1 mg/5 mg/10 mg
| 规格： | 1 mg | 产品价格： | ￥1240.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥5470.0 |
| 规格： | 10 mg | 产品价格： | ￥9690.0 |
Product Introduction
Bioactivity
英文名:Prostaglandin F2α isopropyl ester
描述:PGF2α isopropyl ester is an ester prodrug of PGF2α with enhanced lipid solubility. Due to better membrane penetration, PGF2α isopropyl ester is more suitable than PGF2α or PGF2α tromethamine salt for topical application in studies on intraocular pressure. The ester functionality is readily hydrolyzed in vivo to release the active compound PGF2α. When administered topically to the eyes of cynomolgus monkeys, a 5 μg dose reduces intraocular pressure by 68% after the fourth day of treatment.
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文献和实验useful properties of full phosphoproteins. However, such pTyr-containing peptides have limited use in whole-cell systems resulting from lability of the phosphate ester bond to protein-tyrosine phosphatases (PTPs). For this reason, a number of phosphatase
-inflammatory drugs such as diclofenac did not only suppress the prostaglandin but also the F2 -IsoP pathway. Microdialysis allows the “near-in vivo” measurement of prostanoid mediators, released in the interstitial space of the dermis under inflammatory
Enzyme Immunoassay of Isoprostanes
, and excreted. It is now well recognized that isoprostane levels, most commonly those of 15F2t -isoprostane (formerly denoted 8-iso-prostaglandin F2 α ) in blood or urine, are useful biomarkers for the assessment of oxidative stress, which is a major risk factor
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