- ￥1120 - 8690
- TargetMol
- 美国
- T37939
- 2025年07月04日
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- 详细信息
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
N-Desethyl Bimatoprost
- 库存：
10
- 供应商：
TargetMol
- CAS号：
155205-89-3
- 规格：
10 mg/5 mg/1 mg
| 规格： | 10 mg | 产品价格： | ￥8690.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥4900.0 |
| 规格： | 1 mg | 产品价格： | ￥1120.0 |
Product Introduction
Bioactivity
英文名:N-Desethyl Bimatoprost
描述:N-Desethyl Bimatoprost (17-phenyl trinor PGF2α amide) is an F-series PG analog in which the C-1 carboxyl group has been modified to an unsubstituted amide. PG esters have been shown to have ocular hypotensive activity. PG N-ethyl amides were recently introduced as alternative PG hypotensive prodrugs. Although it has been claimed that PG amides are not converted to the free acids in vivo, studies have shown that bovine and human corneal tissue converts the amides of various PGs to the free acids with a conversion efficiency of about 10-20% relative to the hydrolysis of isopropyl esters. 17-phenyl trinor PGF2α amide would be expected to show the typical intraocular effects of latanoprost, but with the much slower hydrolysis pharmacokinetics of the PG N-amides.
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