Powder: -20°C for 3 years In solvent: -80°C for 2 years
英文名:
C4 Ceramide (d18:1/4:0)
库存:
10
供应商:
TargetMol
CAS号:
74713-58-9
规格:
10 mg/100 mg/50 mg
规格:
10 mg
产品价格:
¥647.0
规格:
100 mg
产品价格:
¥3029.0
规格:
50 mg
产品价格:
¥1668.0
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产品名称:C4 Ceramide (d18:1/4:0) 产品别名:C4 Ceramide (d18:1/4:0);Cer(d18:1/4:0);C4 Ceramide (d18:1/4:0)
产品介绍:C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. [1] [2] [3] It inhibits IL-4 production by 16% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. [1] C4 Ceramide is cytotoxic to SK-BR-3 and MCF-7/Adr breast cancer cells (IC50s = 15.9 and 19.9 μM, respectively). [2] C4 Ceramide also increases maturation and stability of cystic fibrosis transmembrane conductance regulator (CFTR) proteins bearing the F508 deletion (F508del) mutation, enhances cAMP-activated chloride secretion, and suppresses secretion of IL-8 in primary epithelial cells isolated from patients with cystic fibrosis.[3] 纯度:N/A CAS:74713-58-9
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