- ￥14700
- TargetMol
- 美国
- T37523
- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Tenofovir diphosphate (sodium salt)
- 库存：
10
- 供应商：
TargetMol
- 规格：
1 mg
Product Introduction
Bioactivity
英文名:Tenofovir diphosphate (sodium salt)
描述:Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM). It is selective for these enzymes over DNA polymerase α and β, as well as mitochondrial DNA polymerase γ (Kis = 5.2, 81.7, and 59.5 μM, respectively). Tenofovir diphosphate is formed intracellularly through phosphorylation of the prodrugs tenofovir and tenofovir disoproxil by nucleotide kinases. Increased levels of tenofovir diphosphate in isolated peripheral blood mononuclear cells (PBMCs) correlate with a decrease in the risk of simian HIV (SHIV) acquisition in a macaque model of rectal SHIV transmission.
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文献和实验Purification of the Constitutive Nitric Oxide Synthase
(3 ), respectively; all subsequent reports have been modifications of these procedures. The purification of both of the constitutive isoforms and the inducible (i) NOS depends on the use of 2′,5′-adenosine diphosphate (ADP) affinity chromatography. The 2′,5′-ADP
名 称 ADP 全名（英） adenosine diphosphate 全名（中） 二磷酸腺苷 含义 名 称 AG 全名（英） 8-azaguanine 全名（中） 氮杂鸟嘌呤 含义 名 称 AMP 全名（英） adenosine-5'-monphosphate 全名（中） 一磷酸腺苷 含义 名 称 AO 全名（英）
) ADDITIONAL INFO it's possible to bleed mice by cardiac puncture under ether anesthesia. it's possible to collect blood into sodium citrate 3.8% ( 0.1 mol/L ) = 1 vol citrate : 9 vol blood
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