- ￥4880
- TargetMol
- 美国
- T37361
- 2025年07月12日
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- 详细信息
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
6β-hydroxy Dexamethasone
- 库存：
10
- 供应商：
TargetMol
- CAS号：
55879-47-5
- 规格：
2500 μg
Product Introduction
Bioactivity
英文名:6β-hydroxy Dexamethasone
描述:6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound. Dexamethasone is metabolized by CYP3A4; therefore, quantification of the dexamethasone metabolites, 6α- and 6β-hydroxy dexamethasone, can be used to determine CYP3A4 enzyme activity in humans., The formation of 6-hydroxy dexamethasone metabolites is species-specific, with hamsters producing the highest amount. In rats, dexamethasone hydroxylation is sex-specific, with male rats producing metabolites in similar ratios to humans and female rats producing fewer hydroxylated metabolites than male rats.
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