- ￥4390 - 8310
- TargetMol
- 美国
- T37295
- 2025年07月14日
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- 详细信息
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Ganglioside GM1 Asialo Mixture
- 库存：
10
- 供应商：
TargetMol
- CAS号：
71012-19-6
- 规格：
1 mg/500 μg
| 规格： | 1 mg | 产品价格： | ￥8310.0 |
|---|---|---|---|
| 规格： | 500 μg | 产品价格： | ￥4390.0 |
Product Introduction
Bioactivity
英文名:Ganglioside GM1 Asialo Mixture
描述:Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase. Ganglioside GM1 asialo is a glycolipid receptor for P. aeruginosa flagellin and stimulates defensive responses in host cells, including extracellular ATP release, calcium mobilization, and ERK1/2 phosphorylation when stimulated by flagellin and an anti-ganglioside GM1 asialo antibody. The percentage of ganglioside GM1 asialo-positive natural killer (NK) and CD8+ T cells in lung is increased in a mouse model of respiratory syncytial virus (RSV) infection compared with healthy animals. Depletion of ganglioside GM1 asialo-positive NK and T cells reduces IFN-γ levels in the lung, reduces weight loss, and increases lung viral load in RSV-infected mice. Ganglioside GM1 asialo mixture contains ganglioside GM1 asialo molecular species with C18:1 and C20:1 sphingoid backbones.
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