- ￥2180 - 15400
- TargetMol
- 美国
- T37235
- 2025年07月03日
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- 详细信息
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
(±)16(17)-EpDPA
- 库存：
10
- 供应商：
TargetMol
- CAS号：
155073-46-4
- 规格：
100 μg/50 μg/500 μg/25 μg
| 规格： | 100 μg | 产品价格： | ￥5500.0 |
|---|---|---|---|
| 规格： | 50 μg | 产品价格： | ￥3450.0 |
| 规格： | 500 μg | 产品价格： | ￥15400.0 |
| 规格： | 25 μg | 产品价格： | ￥2180.0 |
Product Introduction
Bioactivity
英文名:(±)16(17)-EpDPA
描述:EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators.[1],[2]Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty acids produces epoxides such as (±)14(15)-EET which are prime candidates for the actual active mediator.[3] However, the CYP450 metabolites of eicosapentaenoic acid and docosahexaenoic acid have been little studied relative to arachidonate epoxygenase metabolites. (±)16(17)-EpDPA is the DHA homolog of (±)14(15)-EpETrE, derived via epoxidation of the 16,17-double bond of DHA. The EDHF activity of (±)16(17)-EpDPA has not yet been determined. The epoxygenase metabolites of DHA have also been detected in a mouse inflammation model.[4]
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