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- 详细信息
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
(±)14(15)-EpETE
- 库存:
10
- 供应商:
TargetMol
- CAS号:
131339-24-7
- 规格:
100 μg/25 μg/50 μg/500 μg
| 规格: | 100 μg | 产品价格: | ¥2940.0 |
|---|---|---|---|
| 规格: | 25 μg | 产品价格: | ¥840.0 |
| 规格: | 50 μg | 产品价格: | ¥1550.0 |
| 规格: | 500 μg | 产品价格: | ¥12900.0 |
Product Introduction
Bioactivity
英文名:(±)14(15)-EpETE
描述:EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty acids, produces epoxides such as (±)14(15)-EpETrE which are prime candidates for the actual active mediator. However, the CYP450 metabolites of eicosapentaenoic acid and docosahexaenoic acid have been little studied relative to arachidonate epoxygenase metabolites. (±)14(15)-EpETE is the ω-3 homolog of 14(15)-EpETrE, derived via epoxidation of the 14,15-double bond of EPA. The EDHF activity of (±)14(15)-EpETE has not yet been determined.

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