- ￥132 - 289
- TargetMol
- 美国
- T37219
- 2025年07月10日
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- 详细信息
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
N-Palmitoyl Glycine
- 库存：
10
- 供应商：
TargetMol
- CAS号：
2441-41-0
- 规格：
10 mg/2 mg
| 规格： | 10 mg | 产品价格： | ￥289.0 |
|---|---|---|---|
| 规格： | 2 mg | 产品价格： | ￥132.0 |
Product Introduction
Bioactivity
英文名:N-Palmitoyl Glycine
描述:The acyl amides are a family of endogenous lipids that act as potent modulators of pain and inflammation. The best characterized members of this family are the arachidonoyl amides, which includes N-arachidonoyl ethanolamide (AEA; anandamide). N-palmitoyl glycine (PalGly) contains an 18-carbon saturated fatty acid that is amide-linked to glycine and is structurally similar to the phospholipid-derived N-acyl ethanolamines. Endogenously produced in rat skin and spinal cord, PalGly is present in 100-fold greater amounts in skin and 3-fold greater in brain compared to AEA. Injection of 0.43 μg PalGly in rat hindpaw inhibits heat-induced firing of nociceptive neurons in rat dorsal horn. PalGly treatment induces transient calcium influx in native dorsal root ganglion (DRG) cells and in the PTX-sensitive, DRG-like cell line F-11 (EC50 = 5.5 μM).
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