- ￥192 - 2100
- TargetMol
- 美国
- T37056
- 2025年07月13日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
D-erythro-MAPP
- 库存：
10
- 供应商：
TargetMol
- CAS号：
143492-38-0
- 规格：
10 mg/5 mg/500 μg/1 mg
| 规格： | 10 mg | 产品价格： | ￥2100.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥1220.0 |
| 规格： | 500 μg | 产品价格： | ￥192.0 |
| 规格： | 1 mg | 产品价格： | ￥315.0 |
Product Introduction
Bioactivity
英文名:D-erythro-MAPP
描述:D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 μM) as well as the serine/threonine protein phosphatase CAPP at concentrations up to 10 μM. D-erythro-MAPP increases intracellular ceramide levels, induces cell cycle arrest at the G0/G1 phase, and inhibits growth of HL-60 promyelocytic leukemia cells in a time- and concentration-dependent manner.
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文献和实验MicroArray Pathway Profiler) is a free, stand?alone computer program designed for viewing and analyzing gene expression data on MAPPs representing biological pathways or any other functional grouping of genes. A MAPP is a special file format produced
Lipid Component Quantitation by Thin Layer Chromatography
and nanoemulsions. We illustrate this technique to quantify C6-ceramide (N -hexanoyl-d -erythro-sphingosine) in a nanoemulsion formulation. C6-ceramide is a powerful chemotherapeutic that is poorly soluble in aqueous buffers.
‐1) 4‐Chloro‐5‐iodo‐7H ‐pyrrolo[2,3‐d ]pyrimidine ( S.7 ; see Pudlo et al., ) 2‐Deoxy‐3,5‐di‐O ‐(p ‐toluoyl)‐α‐D‐erythro ‐pentofuranosyl chloride ( S.8 ; see Hoffer
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