- ￥6490
- TargetMol
- 美国
- T36981
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
GSK 591 dihydrochloride
- 库存：
10
- 供应商：
TargetMol
- CAS号：
2320953-89-5
- 规格：
10 mg
Product Introduction
Bioactivity
英文名:GSK 591 dihydrochloride
描述:Potent and selective PRMT5 inhibitor (IC50 = 4 nM). Selective for PRMT5 over a panel of other PRMTs and lysine methyltransferases. Inhibits proliferation of mantle cell lymphoma (MCL) in vitro. To request the negative control for GSK 591, please fill out the SGC 2096 request form on the SGC website.
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文献和实验Expanding Mouse Ventricular Cardiomyocytes Through GSK‐3 Inhibition
.9.1?23.9.10. © 2013 by John Wiley & Sons, Inc. Keywords: cardiomyocyte proliferation; differentiation; isolation; expansion; GSK?3 inhibitor; Wnt/??catenin signaling
v468. chapter 4 WNT 细胞通路 检测细胞GSK3活性与表达水平
-catenin and GSK3 beta. Curr. Biol. 8, 573–581. 17. Itoh, K., Krupnik, V. E., and Sokol, S. Y. (1998) Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin. Curr. Biol. 8, 591–594. 18. Laemmli, U
[资源] 所有的看家基因(housekeeping genes)列表+引物设计服务
NM_006349 Homo sapiens putative cyclin G1 interacting protein (CG1I), mRNA 591 NM_006004 Homo sapiens ubiquinol-cytochrome c reductase hinge protein (UQCRH), mRNA 1285 NM_005787 Homo sapiens Not56 (D. melanogaster)-like protein (NOT56L), mRNA
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