- ￥1760
- TargetMol
- 美国
- T36553
- 2025年07月08日
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- 详细信息
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Thrombin Receptor Peptide Ligand (trifluoroacetate salt)
- 库存：
10
- 供应商：
TargetMol
- 规格：
1 mg
Product Introduction
Bioactivity
英文名:Thrombin Receptor Peptide Ligand (trifluoroacetate salt)
描述:Thrombin receptor peptide ligand is antagonist of the thrombin receptor (EC50s = 16-33 μM to inhibit platelet aggregation in vitro). It inhibits α-thrombin and platelet aggregation induced by thrombin receptor activating peptide in vitro when used at a concentration of 32 μM but does not affect platelet aggregation induced by ADP or collagen. It also inhibits thrombin- and TRAP-induced proliferation of vascular smooth muscle cells (VSMCs). Thrombin receptor peptide ligand (100 μmol/kg bolus, i.v., plus 900 μmol/kg infusion) inhibits arterial thrombosis in a rabbit model of partial carotid artery occlusion without increasing bleeding time.
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