- ￥560 - 2950
- TargetMol
- 美国
- T36166
- 2025年07月09日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
8-iso-15-keto Prostaglandin F2α
- 库存：
10
- 供应商：
TargetMol
- CAS号：
191919-01-4
- 规格：
100 μg/500 μg/1 mg
| 规格： | 100 μg | 产品价格： | ￥560.0 |
|---|---|---|---|
| 规格： | 500 μg | 产品价格： | ￥1620.0 |
| 规格： | 1 mg | 产品价格： | ￥2950.0 |
Product Introduction
Bioactivity
英文名:8-iso-15-keto Prostaglandin F2α
描述:8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2α) is a prostaglandin-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-iso PGF2α is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-iso PGF2α is infused into rabbits. Early in the infusion (within 1-2 minutes) 8-iso -15-keto PGF2α was a major component of the metabolite profile, which was comprised mostly of unmetabolized 8-iso PGF2α. 8-iso -15-keto PGF2α is a vasoconstrictor when tested on the rat isolated thoracic aorta, acting via the TP (thromboxane) receptor.
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文献和实验小鼠8异前列腺素F2α(8-iso-PGF2α)酶联免疫分析
小鼠 8 异前列腺素 F2 α (8-iso-PGF2 α ) 酶联免疫 分析（ ELISA ） 试剂 盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定小鼠血清，血浆及相关液体样本 中 8异前列腺素F2α(8-iso-PGF2α) 的 含量。 实验原理 ： 本试剂盒应用双抗体夹心法测定 标本 中 小鼠 8 异前列腺素 F2 α (8-iso-PGF2 α ) 水平。用纯化的 小鼠 8 异前列腺素 F2 α
-inflammatory drugs such as diclofenac did not only suppress the prostaglandin but also the F2 -IsoP pathway. Microdialysis allows the “near-in vivo” measurement of prostanoid mediators, released in the interstitial space of the dermis under inflammatory
Enzyme Immunoassay of Isoprostanes
, and excreted. It is now well recognized that isoprostane levels, most commonly those of 15F2t -isoprostane (formerly denoted 8-iso-prostaglandin F2 α ) in blood or urine, are useful biomarkers for the assessment of oxidative stress, which is a major risk factor
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