- ￥560 - 2950
- TargetMol
- 美国
- T36166
- 2025年07月09日
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- 详细信息
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
8-iso-15-keto Prostaglandin F2α
- 库存：
10
- 供应商：
TargetMol
- CAS号：
191919-01-4
- 规格：
100 μg/500 μg/1 mg
| 规格： | 100 μg | 产品价格： | ￥560.0 |
|---|---|---|---|
| 规格： | 500 μg | 产品价格： | ￥1620.0 |
| 规格： | 1 mg | 产品价格： | ￥2950.0 |
Product Introduction
Bioactivity
英文名:8-iso-15-keto Prostaglandin F2α
描述:8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2α) is a prostaglandin-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-iso PGF2α is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-iso PGF2α is infused into rabbits. Early in the infusion (within 1-2 minutes) 8-iso -15-keto PGF2α was a major component of the metabolite profile, which was comprised mostly of unmetabolized 8-iso PGF2α. 8-iso -15-keto PGF2α is a vasoconstrictor when tested on the rat isolated thoracic aorta, acting via the TP (thromboxane) receptor.
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