- ￥1080 - 7840
- TargetMol
- 美国
- T35955
- 2025年07月10日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
PAR2 (1-6) amide (human) (trifluoroacetate salt)
- 库存：
10
- 供应商：
TargetMol
- CAS号：
2379569-17-0
- 规格：
25 mg/5 mg/50 mg/10 mg
| 规格： | 25 mg | 产品价格： | ￥4180.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥1080.0 |
| 规格： | 50 mg | 产品价格： | ￥7840.0 |
| 规格： | 10 mg | 产品价格： | ￥1970.0 |
Product Introduction
Bioactivity
英文名:PAR2 (1-6) amide (human) (trifluoroacetate salt)
描述:PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-length sequence.1It binds to NCTC 2544 cells expressing human PAR2 (Ki= 9.64 μM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50= 0.075 μM).2PAR2 (1-6) amide (100 μM) reduces colony formation of A549 lung cancer cells.1It induces superoxide production and degranulation in isolated human eosinophils when used at a concentration of 500 μM.3PAR2 (1-6) amide (5 μmol/kg) induces tear secretion in rats when used in combination with amastatin .4
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文献和实验Application of Amide Proton Exchange Mass Spectrometry for the Study of Protein‐Protein Interactions
describes amide proton exchange experiments that probe for changes in solvent accessibility at protein?protein interfaces. The simplest version of the protocol, termed the ?on?exchange? experiment, detects protein?protein interfaces by taking advantage
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