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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
2-Thiouridine
- 库存:
10
- 供应商:
TargetMol
- CAS号:
20235-78-3
- 规格:
100 mg
Product Introduction
Bioactivity
英文名:2-Thiouridine
描述:2-Thiouridine (s2U) is a modified nucleobase found in tRNAs that is known to stabilize U:A pairs and modestly destabilize U:G wobble pairs. Modified nucleobases, including 2-thiouridine, are used to study nucleic acid structure and function as well as to engineer novel RNA-based biomolecules.

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文献和实验缩写 s4 U。是存在于原核生物的 tRNA中的微量碱基,占据从 5′末端第 8位的特定位置。其特征是在 330毫微米处有最大的吸收。
RNA with 4-thiouridine to study the molecular mechanisms governing RNA synthesis, processing, and decay.
Introduction of Hypermodified Nucleotides in RNA
methylaminomethyl-2-thiouridine (mnm5 s2 U), methylcarboxymethyl-2-thiouridine (mcm5 s2 U), and 2-thiomethyl-N -6-carbamoylthreonyl-adenosine (ms2 t6 A). We also describe methods for using these nucleoside phosphoramidite reagents to synthesize RNA oligonucleotides
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